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Context
MicroRNAs (miRNAs) finely tune messenger RNA (mRNA) expression. As the brain is a highly heterogeneous tissue, physiologically relevant miRNA expression profiling greatly benefits from sampling brain regions or nuclei. MiRNA expression profiling from individual samples is also important for investigating potential differences between animals according to their physiological and pathophysiological status[1].
[1] L.Amar et al., MicroRNA expressionprofiling of hypothalamic arcuate andparaventricular nuclei from single rats using Illumina sequencing technology;Journal of Neuroscience Methods;http://dx.doi.org/10.1016/j.jneumeth.2012.05.033
